We founded Begin Rebirth with a simple belief: the microbiome is not just a system — it is a story of self. We translate validated science into next-generation probiotics, prebiotics, and postbiotics—designed to support the human body from the earliest moments of life through every stage that follows. Grounded in research, guided by care, we’re setting a new standard for microbial therapeutics—quietly reshaping the way we think about health, from the inside out.

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RE-1™ Benefits Beyond

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RE-1™ Benefits Beyond

Our flagship innovation, RE-1™ Eubiotic, is now available for your healthcare practice. Developed from a deep understanding of the complex interactions within the microbiome, our metagenomic selected medical-grade Eubiotic (500 Billion CFU) is formulated for whole body benefits and immune protection, with 7 distinct, clinically and scientifically studied probiotic strains, two synergistic prebiotics and one immunogenic postbiotic.*

RE-1™ is the first medical-grade 3-in-1 prebiotic + probiotic + postbiotic with Human Origin Strains (HOSt™) and 4.5g fiber (GOS & Inulin) clinically-validated to rapidly restore the microbiome and protect the immune-system from daily-disruptions. Formulated with strains that preserve ecosystem function, fortify the gut barrier, promote healthy regularity, reinforce an optimal gut-skin axis, promote cardiovascular health, and support healthy immunological responses in the GI tract.*
We select proven probiotic strains backed by human clinical research, to ensure efficacy, proven safety, and enduring potency—ensuring every dose delivers measurable benefits.

With 500 Billion CFU consisting of 8 distinct Human Origin Strains HOSt, RE-1™ contains significantly more unique microbial genes compared to other probiotics, providing high versatility, and functionality to deliver broad-spectrum benefits to your patients.
RE-1™ stands on a foundation of rigorous scientific validation, with over 50 years of research and 200 + Studies validating our strain-specific benefits. We have also completed a third-party, non-randomized, single-arm study: Conducted on 35 adults ages 25-65 assessing the self-perceived efficacy of RE-1™ over 7 days. RE-1™ has no serious adverse effects and is efficacious for supporting gastrointestinal health through ease of evacuation, bloating, gas production, abdominal pain, serotonin production, and the recovery of low-abundance species during and after a course of broad-spectrum antibiotics.
A synergistic duo of both Galactooligosaccharide (GOS) and Inulin (Low Molecular Weight LMW) provides both immediate and sustained benefits to the gut microbiome. With 4.5g of fiber per serve—to foster the growth of beneficial metabolites throughout the microbiome.
Our trademarked Lysosublime™ delivery requires no breakdown of a capsule barrier, ensuring fastest absorption throughout the entire gastrointestinal tract. Lyosublime™ delivery also concentrates higher quantities of microbes to improve biological efficacy—500 billion CFU, ensuring maximum potency to deliver optimum benefits. Lyosublime™ also serves as a barrier to oxygen, moisture, and heat stress to minimize impact from fluctuating shipping and storage conditions. No refrigeration is required.*
We conduct extensive verifications on RE-1™, including a suite of third-party testing throughout the manufacturing process. Our tests includes:

- Potency (CFU)
- Contaminants (heavy metals and pesticides)
- Extended allergen panel (all 14 EFSA-defined classes)
- Thermostability (temperature)

With quality assurance and quality control (QA / QC) checkpoints, we monitor purity under both US and European protocols (including cGMP + HACCP) throughout the production cycle. This means we extensively test each ingredient batch during manufacture.

RE-1™ undergoes whole-genome sequencing to provide precise verification of probiotic species and assure the absence of antibiotic-resistant genes. This important step ensures quality, purity, and specificity.

Select Clinical + Community Partners

Robin Lim, Midwife

Robin Lim, Midwife

2011 CNN Hero of the Year

Gobind Vashdev, Author

Gobind Vashdev, Author

Breathwork Practitioner

Dr Nofrina Arifin, MD

Dr Nofrina Arifin, MD

Board-Certified Dermatologist

Michelle Hansen, Therapist

Michelle Hansen, Therapist

Women's Health & Immunology

Microbial Innovation
From Discovery to Impact

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We are a collective of scientists, clinicians, designers, and storytellers—united by a shared pursuit: to reimagine health through the unseen lens of the microbiome.

We translate scientific breakthroughs into valuable innovations, living medicines—and ecological interventions that restore balance when it has been lost.

Our research spans systems within and beyond the human body: the gut, the skin, the mouth, the mind, the immune system—all the fragile ecosystems that sustain us. Through Begin Rebirth, we explore impactful solutions for global human protection.

Because health is not singular. It is shared. And protection—of life, of planet, of future—begins here.

FAQs

Join our Practitioner Program to access wholesale pricing, exclusive clinical resources, and patient education tools. We provide ongoing support, training, and marketing assets so you can confidently integrate RE-1™ into your practice and deliver proven gut-health results.

Our detailed protocols guide you in prescribing RE-1™ for a wide range of complex digestive and immune concerns. Each protocol includes optimal dosing, duration, and patient guidance to maximise results. Whether for acute relief or long-term microbiome restoration, our usage recommendations are designed for safety, efficacy, and seamless integration into your existing treatment plans.

RE-1™ is made in Japan to the highest global standards, with every batch tested for potency, purity, and safety. Our formula is free from allergens, fillers, additives, and GMOs, and is third-party verified for quality and stability. Suitable for all ages over three and all dietary requirements, RE-1™ is designed for safe daily use in both acute and long-term protocols.

RE-1™ is built on more than five decades of microbiome research and over 200 peer-reviewed studies. Its HOSt® strains and synergistic prebiotic–postbiotic matrix have been clinically shown to improve digestive function, enhance immunity, and support whole-body health. Our practitioner materials include detailed research summaries, making it easy to integrate evidence-based gut restoration into patient care.

Every batch of RE-1™ undergoes rigorous third-party validation to confirm potency, purity, and strain identity. We use whole-genome sequencing, allergen screening, heavy metal testing, and stability analysis to ensure uncompromising quality. This independent verification gives practitioners and patients complete confidence that each dose delivers exactly what the label promises — nothing more, nothing less.

Real clinicians, here to support.

We are here to help you integrate RE-1™ into your practice.

Ready to learn more?

Access practitioner resources, and your complimentary RE-1™ product trial.